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Symbol
Name
ID
Myc
myelocytomatosis oncogene
MGI:97250
Phenotype annotations related to digestive/alimentary system
Darker colors indicate more annotations
Human Phenotypes
Gastrointestinal hemorrhage
Intestinal obstruction
Nausea and vomiting
Disease(s) Associated with MYC
Burkitt lymphoma

Mouse Phenotypes
abnormal intestinal goblet cell morphology
abnormal enterocyte proliferation
abnormal intestinal enteroendocrine cell morphology
abnormal pancreatic acinus morphology
abnormal pancreatic acinar cell morphology
absent pancreatic acinar cells
abnormal pancreatic duct morphology
exocrine pancreas atrophy
abnormal intestine morphology
abnormal large intestine crypts of Lieberkuhn morphology
abnormal small intestine crypts of Lieberkuhn morphology
decreased Paneth cell number
decreased small intestinal villus size
abnormal enterocyte physiology
Availability Mouse Genotype
Myctm1.1Itl/Myctm1.1Itl
Tg(Ela1-Myc)158Bri/0
Tg(Ela1-Myc)159Bri/0
Tg(Ela1-Myc)160Bri/0
Myctm2.1Atp/Myctm2.1Atp
Tg(Pdx1-cre)1Herr/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory